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KMID : 0381919820120010049
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Korean Journal of Microscopy
1982 Volume.12 No. 1 p.49 ~ p.56
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Ultrastructure of Cryptococcus neoformans in the Skin Tissue
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Kwon Tae-Jung
Kim Chung-Sook
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Abstract
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A case of systemic cryptococcosis developed in 4 year old boy was described and illustrated by light and electron microscope. Light microscopically, the upper dermis of the skin showed chronic nonspecific inflammation with numerous spherical spores surrounded by a clear halo created by the wide gelatinous capsule. Ultrastructurally, the C. neoformans showed the wide capsule containing microfibrils that appeared to radiate from the cell wall and to coil and interwine in various directions. The cell was uninucleate with a single nucleolus. Along the inner nuclear envelope, numerous small vesicles were present. In addition, C. neoformans presented membranous organelles derived from the plasma membrane and comparable to bacterial mesosomes.
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